Encyclopedia of the Alkaloids Volume 4

Volume 4 of the Encyclopedia of the Alkaloids covers the literature to the end of 1981 and includes those compounds which have been discovered since Volume 3 was published in 1977. There is also a small number of entries giving recently determined structure or addi- tional information regarding alkaloids given in the preceding three volumes. It is a great pleasure to thank the staff of the John Rylands Science Library of the Univer- sity of Manchester for kindly providing me with access to the literature on this subject. Woodhouses, JOHN S. GLASBY Manchester, England May, 1982 Contents A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . I N . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251 B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 0 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 262 C . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 P . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273 0 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108 Q . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299 E . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 R . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300 F . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152 S . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31O G . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158 T . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 339 H . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 U . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 358 I . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 V . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361 J . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 W . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 367 K . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 210 X . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368 L . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217 Y . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369 M . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 Z . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 370 Formula Index. . . . . . . . . . . . . . . . . . . . 371 A ACETYLALLOYOHIMBINE (Alkaloid NRB6) C23H2SN203 M. p. Indefinite I I OAc The root bark of Rauwolfia nitida yields this yohimbine-type alkaloid which has been ob- tained as an off-white amorphous powder having no definite melting point. The base is lae- 2 vorotatory with a specific rotation of [aJ5 -89 (c 0. 01, CHCI ) and gives an ultraviolet 3 spectrum in MeOH with absorption maxima at 225,284 and 290 nm. The structure has been established from chemical and spectroscopic analysis. M. A. Amer, W. E. Court, Phytochem., 20,2569 (1981) 14-ACETYLBROWNINE ___: (OMe M. p.